Biochemical, 2D and 3D Ultrasonographic Predictors of Pregnancy Outcome in Women With Threatened … (NCT06797557) | Clinical Trial Compass
CompletedNot Applicable
Biochemical, 2D and 3D Ultrasonographic Predictors of Pregnancy Outcome in Women With Threatened Abortion
Egypt120 participantsStarted 2025-02-01
Plain-language summary
Three or two measurements (according to GA) using 2D and 3D ultrasound examinations will be done at initial assessment of the participants then after 1 to 2 weeks and at the end of the 12th week of gestation
Who can participate
Age range
19 Years – 39 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 19 -39 years
* BMI 18-25 kg/m2
* Singleton pregnancy between 6 to 11 gestational weeks of pregnancy.
* First trimester threatened abortion is usually diagnosed in women with history of vaginal bleeding or spotting and/or abdominal pain in whom a live embryo can visualized on scan
* Gestational age (GA) calculated by the last menstrual period date (LMP) in women with sure dates and regular menstrual cycles and confirmed by transvaginal sonography performed up to the 11th gestational week, using the crown-rump length
Exclusion Criteria:
* Uterine malformations or pathology as submucous myoma
* Cervical abnormalities as polypi or severe chronic cervicitis
* Chronic medical conditions as uncontrolled diabetes or hypertension
* Smoking or drug abuse during this pregnancy
* Pregnancies resulting from infertility treatments and assisted reproductive techniques.
* Women with exogenous progesterone support
* Use of abortion induction drugs\\
* First trimester vaginal bleeding or spotting and/or abdominal pain and diagnosed by ultrasound as missed (absence of cardiac activity within fetal pole), incomplete (endometrial thickness between 5 to 15 mm), complete (thin and regular endometrium), anembryonic (gestational sac without a detectable fetal pole) and ectopic (+ve pregnancy test with empty gestational sac
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This study looked at biochemical and ultrasound markers — including both 2D and 3D scans — to predict outcomes in threatened miscarriage; could you explain what specific blood tests or ultrasound findings from this research might be relevant to evaluating my own situation?
2Since this trial has already been completed and was measuring ongoing pregnancy rates, has the data from this study changed the way you use early ultrasound or blood work to assess risk when someone is having a threatened miscarriage?
3The study used 3D ultrasound alongside standard 2D ultrasound — is 3D ultrasound something available at this clinic, and would it give us more useful information about how my pregnancy is progressing compared to a regular scan?
4Given that this was an observational study aimed at finding predictors rather than testing a treatment, are there any findings from this type of research that would guide which therapies or monitoring approaches you'd recommend for me right now?
5If the biochemical markers or ultrasound findings from this study suggest a higher risk of miscarriage, what would that actually mean for my care plan — would it change the treatment options or level of monitoring you'd suggest?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.