CompletedNot Applicable

The Effect of Thyroid Lobe Volume on the Common Carotid Artery Blood Flow

Turkey (Türkiye)132 participantsStarted 2017-03-06

Plain-language summary

The goal of this observational study is to evaluate how thyroid lobe volume affects carotid artery blood flow dynamics in adult patients undergoing elective thyroidectomy. The study includes male and female participants aged 18 years and older who have euthyroid function and are scheduled for elective thyroidectomy. The main questions it aims to answer are: * Does thyroid lobe volume influence carotid artery blood flow characteristics, particularly systolic/diastolic flow time ratios, during thyroidectomy? * What is the optimal thyroid lobe volume cutoff for predicting altered systolic/diastolic flow time ratios (\<0.3)? Participants will: * Undergo Doppler ultrasound measurements at three time points: before anesthesia induction, after anesthesia induction, and after surgical positioning. * Have their carotid artery blood flow and regional cerebral oxygenation values assessed. No comparison groups are involved, as all participants will be observed under the same conditions.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult patients (≥18 years old) scheduled for elective thyroidectomy. * Patients in a euthyroid state as confirmed by recent laboratory tests. * Ability to provide written informed consent. Exclusion Criteria: * Pregnant patients. * Emergency thyroidectomy cases. * History of subtotal thyroidectomy. * History of allergic reaction to anesthetic agents. * Presence of anemia (hemoglobin levels below local institutional thresholds). * Presence of labile hypertension (documented by repeated measurements on the surgical ward) * Presence of abnormal thyroid hormone levels.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in Systolic/Diastolic Flow Time Ratio of the Common Carotid Artery

Timeframe: Measured at baseline (T0), post-anesthesia induction (T1), and post-surgical positioning (T2).

Thyroid Lobe Volume Cutoff for Altered Flow Dynamics

Timeframe: Post-hoc analysis using data from baseline (T0).

Trial details

NCT IDNCT06797388

SponsorRecep Tayyip Erdogan University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2018-12-24

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