Effects of Allogenic Umbilical Cord-Derived Mesenchymal Stem Cells on Patients With Rotator Cuff … (NCT06794294) | Clinical Trial Compass
RecruitingPhase 1/2
Effects of Allogenic Umbilical Cord-Derived Mesenchymal Stem Cells on Patients With Rotator Cuff Disease
South Korea21 participantsStarted 2025-01-17
Plain-language summary
The purpose of this study is to evaluate safety and efficacy of Allogenic Umbilical Cord-derived Mesenchymal Stem Cell in Patients with Rotator Cuff Disease
Who can participate
Age range19 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Male or female 19 years of age and older.
* Patients with unilateral shoulder pain lasting for at least 3months
* Patients who do not respond to conservative treatment.
* Patients who have not responded to sufficient non-surgical treatments, including medication, injection therapy, physical therapy, or exercise therapy, for more than 3 months
* Patients who have a partial-thickness rotator cuff tear confirmed with magnetic resonance imaging (MRI) or ultrasonography (US).
* Patients without any restrictions on clinical trial procedures, including hospitalization.
Exclusion Criteria:
* Patients who have received subacromial injection therapy on the affected shoulder within the past 3 months.
* Patients who have undergone rotator cuff surgery on the affected shoulder within the past 6 months
* Patients with a history of receiving stem cell therapy for the shoulder.
* Patients with the following shoulder conditions: complete rotator cuff tear, adhesive capsulitis, or isolated acromioclavicular joint arthropathy.
* Patients showing or suspected of having the following radiological findings: malignancy, severe osteoarthritis of the glenohumeral joint, or skeletal abnormalities decreasing the subacromial space.
* Patients presenting with symptomatic cervical spine disorders.
* Patients with concurrent bilateral shoulder pain
* Patients with polyarthritis, infectious arthritis, rheumatoid arthritis, or fibromyalgia.
* Patients with neurological deficit
* Preg…