Not Yet RecruitingNot Applicable

Paediatric Breakthrough Pain Assessment

210 participantsStarted 2025-01-20

Plain-language summary

Many children and young people with life-limiting and life-threatening illnesses get sudden bursts of pain called breakthrough pain. At the moment, there aren't any good ways to measure this pain in children and young people. The investigators are developing two questionnaires to help: one for patients to fill out themselves and another for parents or healthcare professionals to complete for younger children and young people who cannot explain their pain for themselves. The investigators plan to work with 210 people across hospitals and hospices in England and Wales. This includes children and young people with life-limiting and life-threatening illnesses, their caregivers, and healthcare professionals. The investigators have already made a first version of the questionnaires. The project has three main Studies: In Study 1, the investigators will talk to 5-10 young patients and 5-10 caregivers about their experiences with breakthrough pain. The investigators will use their feedback to improve the questionnaires. In Study 2, the investigators will ask 5-10 patients, 5-10 caregivers, and 5-10 healthcare professionals to fill out the questionnaires while speaking their thoughts out loud. This will help the investigators find any parts that are confusing or difficult to understand. In Study 3, the investigators will test how well the questionnaires works. 80 patients, 40 caregivers, and 40 healthcare professionals will complete the questionnaires three different times to make sure they measure breakthrough pain as accurately as possible. These questionnaire will be useful for hospitals and hospices across England and Wales to help them better manage pain, including breakthrough pain, in patients aged 3 months to 25 years who have life-limiting and life-threatening illnesses.

Who can participate

Age range8 Years – 99 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Children and young people aged 8-25 years who have experienced 1) background pain related to a life limiting or life threatening condition and 2) around-the-clock analgesia prescribed for the previous week, as confirmed by their healthcare team (Studies 1, 2, and 3). * Children and young people must be able to communicate and read in English at a level close to, or in line with their chronological age. * For study 1, non-verbal children and young people, or those with limited verbal ability, will be recruited if they are happy to participate using the Microsoft Teams chat function. * Parents and caregivers of children and young people aged 3-month-25-years who have experienced 1) background pain related to a life limiting or life threatening condition and 2) around-the-clock analgesia prescribed for the previous week, as confirmed by their healthcare team. (Studies 1, 2, and 3). * Caregivers can be caring for verbal, non-verbal, or pre-verbal children with or without cognitive or developmental difficulties of any level. * Parents and caregivers must have self-reported full or partial responsibility for assessing the child or young person's pain. * Healthcare professionals in primary, secondary and tertiary care who are involved in the care of children and young people with life limiting or life threatening conditions (Studies 2 and 3). Exclusion Criteria: * • Children, young people, parents and caregivers with limited ability to communicate and read i…

What they're measuring

Diagnostic accuracy of the Breakthrough Pain Assessment Questionnaire (BTPAQ)

Timeframe: From participant enrollment in Study 3 through completion of the final assessment up to 4 weeks later

Test-retest reliability of the Breakthrough Pain Assessment Questionnaire (BTPAQ)

Timeframe: From participant enrolment in Study 3 through completion of the second assessment 24 hours later

Trial details

NCT IDNCT06790719

SponsorUniversity of Southampton

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-12

Contact for this trial

Georgia Turner, BSc

+44 23 8059 9660 beacon@soton.ac.uk

View on ClinicalTrials.gov More Breakthrough Pain trials