By InvitationNot Applicable

Intradialysis Exercise Functional Capacity, Body Composition and Survival in Hemodialysis Patients

Mexico50 participantsStarted 2025-01-20

Plain-language summary

Chronic kidney disease and renal replacement treatments (hemodialysis, peritoneal dialysis, kidney transplant) produce various alterations at the level of muscle, bones, fat content and the heart; can alter physical capabilities such as muscle strength, resistance to climb a step repeatedly intensely, and the ability to move the joints freely, in addition to producing an increase or decrease in weight and alterations in its distribution (for example, decreasing muscle and increase fat). The above, added to the particular factors of hemodialysis such as the reduction in daily time to exercise due to the sessions, or the fatigue after it, can together generate greater repercussions on functional capacity and thus increase the risk of suffering from cardiovascular problems. and accelerate the evolution of the disease. Therefore, this study aims to determine the effect of a 12-week supervised physical exercise program during hemodialysis on strength and ability to move, the amount of fat and muscle in the body, as well as bone wear. ; and compare these results with a group of patients who do not perform supervised exercise. In addition, it will be determined how exercise can act in the long term, preventing the risk of hospitalization and death due to cardiovascular causes. The above is useful in order to establish recommendations and protocols that help us increase the quality of life and survival of the person.

Who can participate

Age range18 Years – 50 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Male and female patients aged between 18-50 years.
✓. Patients who receive regular hemodialysis sessions 3 times a week, reported through the clinical record.
✓. Patients with a clinical history of being treated with HD for at least 1 previous year (reported by clinical record).
✓. Patients without a history of myocardial infarction in the last 3 months (reported by clinical record).
✓. Patients who are not in a kidney transplant protocol to be performed during the next 12 months.
✓. Patients who have permission from their nephrology specialist to participate.
✓. Patients who agree to participate in the study, and who voluntarily sign the informed consent (IC) form.
✓. Patients without a history of coronary artery disease in the last 4 months (reported by clinical record).

Exclusion criteria

✕. If the patient presents any disease, or neurological, respiratory or skeletal muscle disorder during the development of the physical capacity tests, or during the execution of the protocol, which is aggravated by the practice of physical exercise.

What they're measuring

Handgrip strength

Timeframe: This test will be measured before starting the intervention with intradialysis exercise and 12 weeks after the start of the same.

Cardiorespiratory capacity

Timeframe: This test will be measured before starting the intervention with intradialysis exercise and 12 weeks after the start of the same.

Lower limb functionality:

Timeframe: This test will be measured before starting the intervention with intradialysis exercise and 12 weeks after the start of the same.

Body Weight

Timeframe: This test will be measured before starting the intervention with intradialysis exercise and 12 weeks after the start of the same.

Height

Timeframe: This test will be measured before starting the intervention with intradialysis exercise and 12 weeks after the start of the same.

Waist circumference

Timeframe: This test will be measured before starting the intervention with intradialysis exercise and 12 weeks after the start of the same.

Body Mass Index

Timeframe: This test will be measured before starting the intervention with intradialysis exercise and 12 weeks after the start of the same.

Trial details

NCT IDNCT06788054

SponsorUniversidad de Guanajuato

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-08-30

View on ClinicalTrials.gov More Hemodialysis trials

Plain-language summary

Who can participate

Age range18 Years – 50 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Male and female patients aged between 18-50 years.
✓. Patients who receive regular hemodialysis sessions 3 times a week, reported through the clinical record.
✓. Patients with a clinical history of being treated with HD for at least 1 previous year (reported by clinical record).
✓. Patients without a history of myocardial infarction in the last 3 months (reported by clinical record).
✓. Patients who are not in a kidney transplant protocol to be performed during the next 12 months.
✓. Patients who have permission from their nephrology specialist to participate.
✓. Patients who agree to participate in the study, and who voluntarily sign the informed consent (IC) form.
✓. Patients without a history of coronary artery disease in the last 4 months (reported by clinical record).

Exclusion criteria

✕. If the patient presents any disease, or neurological, respiratory or skeletal muscle disorder during the development of the physical capacity tests, or during the execution of the protocol, which is aggravated by the practice of physical exercise.

What they're measuring

Handgrip strength

Timeframe: This test will be measured before starting the intervention with intradialysis exercise and 12 weeks after the start of the same.

Cardiorespiratory capacity

Timeframe: This test will be measured before starting the intervention with intradialysis exercise and 12 weeks after the start of the same.

Lower limb functionality:

Timeframe: This test will be measured before starting the intervention with intradialysis exercise and 12 weeks after the start of the same.

Body Weight

Timeframe: This test will be measured before starting the intervention with intradialysis exercise and 12 weeks after the start of the same.

Height

Timeframe: This test will be measured before starting the intervention with intradialysis exercise and 12 weeks after the start of the same.

Waist circumference

Timeframe: This test will be measured before starting the intervention with intradialysis exercise and 12 weeks after the start of the same.

Body Mass Index

Timeframe: This test will be measured before starting the intervention with intradialysis exercise and 12 weeks after the start of the same.