RecruitingPhase 2/3

"The Effect of Inhaled Nitroglycerin for COPD Patients

Egypt40 participantsStarted 2025-02-01

Plain-language summary

this study aims to investigative the benefits of using nebulized nitroglycerin in improving respiratory functions in patients of late stage COPD

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult patient's ≥ 18 years old COPD exacerbation with respiratory failure and Echo evidenced presence of pulmonary hypertension (defined as mean pulmonary artery pressure \> 20 mmHg) Exclusion Criteria: * Profound left ventricular failure, as the decrease in pulmonary vascular resistance results in an increase in left ventricular preload. This may worsen cardiogenic pulmonary edema. * Pregnant female patients * Patient with hypersensitivity to nitroglycerin

What they're measuring

Change in pulmonary functions

Timeframe: 5 days after start of nebulized nitroglycerin

Trial details

NCT IDNCT06785337

SponsorBeni-Suef University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-10-01

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