CompletedNot Applicable

Comparative Study of Fentanyl vs Dexmedetomidine as Adjuvants to Intrathecal Bupivacaine in Cesarean Section

Egypt60 participantsStarted 2024-03-01

Plain-language summary

The quality of the spinal anesthesia has beenreported to be improved by the addition of opioids (such as morphine, fentanyl and sufentanil) and other drugs (such as dexmedetomidine, clonidine, magnesium sulfate (Mg), neostigmine, ketamine, and midazolam). Opioids such as fentanyl in combination with bupivacaine improvesthe quality of intraoperative and early postoperative subarachnoid block. Although, fentanylensures superior quality of analgesia, it is associated with many side effects. This has directed theresearch toward the use of newer and betteradjuvants for spinal anesthesia such as clonidineand dexmedetomidine

Who can participate

Age range18 Years – 40 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Pregnant women in the childbearing period * aged 18 to 40 years * Gestational age ≥37 weeks of pregnancy * ASA I and II candidates for elective cesarean section under spinal anesthesia. Exclusion Criteria: * The patients with emergency conditions, * Contraindication of spinal anesthesia, * History of valvular heart disease, * History of allergy or sensitivity to applied drugs and * Patients with placenta previa * Failed blockade or need for induction of general anesthesia

What they're measuring

Pain Relief

Timeframe: from 0 hours to 6 hours after the procedure

Trial details

NCT IDNCT06785285

SponsorSohag University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-10-01

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