Effects of Resistance Training on Sarcopenia in Older Patients With Chronic Heart Failure (NCT06785168) | Clinical Trial Compass
CompletedNot Applicable
Effects of Resistance Training on Sarcopenia in Older Patients With Chronic Heart Failure
Vietnam146 participantsStarted 2025-01-27
Plain-language summary
The goal of study is to evaluate the effects of an eight-week machine-based resistance training program on managing sarcopenia in older outpatients with chronic heart failure (HF) at Military Hospital 175.
Who can participate
Age range
60 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Aged ≥ 60 years old
* Meet the diagnostic criteria of 2019 AWGS2 sarcopenia, can be diagnosed once meeting (1) + (2) or (1) + (3) or (1) + (2) + (3): (1) Appendicular skeletal muscle mass (ASM): dual-energy X-ray absorptiometry (DXA) (male \<7.0 kg/m², female \<5.4 kg/m²). (2) Muscle strength: handgrip strength (male \<28.0 kg, female \<18.0 kg). (3) Physical performance: 6-meter walking speed \<1.0 m/s.
* Meet the diagnostic criteria of heart failure following ESC 2021.
* Clearly understand the content and purpose of the study and sign the informed consent form.
Exclusion Criteria: There are contraindications for Exercise Testing in patients with stable heart failure according to ACSM 2022:
* Early stage after acute coronary syndrome (within the first 2 days)
* Unstable coronary artery disease
* Decompensated heart failure
* Acute venous thrombosis or recent arterial embolism (pulmonary or systemic)
* Acute myocarditis, pericarditis, endocarditis
* Aortic dissection of the valve
* Severe symptomatic aortic stenosis
* Acute systemic disease or fever
* Uncontrolled or life-threatening atrial or ventricular arrhythmias (including new-onset atrial fibrillation or flutter)
* Uncontrolled tachycardia (resting heart rate \> 120 beats per minute)
* Third-degree AV block
* Uncontrolled diabetes
* Symptomatic orthostatic hypotension (\> 20 mmHg)
* Gradually increasing fatigue during exercise or dyspnea at rest or with exertion within the past 3-5 days
* Signif…
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is specifically for older patients who have both sarcopenia and chronic heart failure — given my particular situation and how well my heart failure is currently managed, do you think I would have been a realistic candidate for something like this?
2Since this study is listed as 'active, not recruiting,' it's no longer enrolling new patients — are there any similar resistance training programs or ongoing trials focused on muscle loss in heart failure that I could still access or join?
3The trial is measuring changes in muscle strength as its main outcome — how important is improving muscle strength compared to other aspects of sarcopenia like muscle mass or physical function, and what would that mean for my day-to-day life?
4Resistance training in someone with chronic heart failure sounds like it could carry some risks — what does my doctor think about the safety of structured exercise programs for my level of heart failure, and how would we monitor for any warning signs?
5If results from this kind of trial show that resistance training helps with muscle loss in heart failure patients, would that change how my care team might approach my treatment plan, or is there already evidence supporting exercise as part of managing my condition?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.