Evaluation of NV701 (Pilocarpine 1.25%) Compared With Vuity (Pilocarpine 1.25%) on Pupil Size in Subjects With Presbyopia

Inclusion Criteria: * Age 40-55 years with presbyopia * Able to understand and willing to sign the informed consent for the study * Resting mesopic pupil diameter of \>4 mm in both eyes * Change in mesopic pupil diameter of \>1 mm after 1 hour in response to pilocarpine 1.25% in both eyes * Willing to abstain from contact lens use for 7 days before the study visit * Women of childbearing age must have a negative urine pregnancy test at the screening visit and be willing to use a reliable method of birth control during the study Exclusion Criteria: * Anisocoria \>1 mm in photopic or mesopic conditions * High myopia (-6.00 diopters or greater) * Any iris abnormality making it difficult to judge pupil diameter as determined by the principal investigator * Known allergy to any of the study products or medications * Concurrent use of any topical prescription ophthalmic products * History of uveitis or intraocular inflammation * Inability to complete any of the study procedures * History of ocular surgery other than LASIK or PRK * History of retinal tear or retinal detachment * Presence of retinal lattice degeneration, operculated hole, or other retinal pathology on screening exam. * History of punctal plugs or punctal cautery in one or both eyes * History of nasolacrimal duct surgery in one or both eyes * History of blepharoplasty or ptosis surgery in one or both eyes * History of glaucoma, glaucoma suspect or ocular hypertension diagnosis * History of acute angle closure or la…