Use of Pyrvinium to Reverse Stomach Precancerous Conditions

Inclusion Criteria: * The subject is at least 21 years of age. * The subject has histologically proven extensive/marked intestinal metaplasia and/or dysplasia. * The subject is willing and able to provide signed and dated patient informed consent form indicating that he/she has been informed of all pertinent aspects of the study. Exclusion Criteria: * The subject has an active gastric cancer diagnosis. * The subject is pregnant. * The subject has a high-risk of bleeding complications due to anticoagulants or underlying medical condition such as bleeding disorders in whom biopsies are contraindicated. * The subject has impaired renal function. * The subject has impaired hepatic function. * The subject has fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase deficiency. * The subject has chronic bowel disease. * The subject has any other severe acute or chronic medical or psychiatric condition or laboratory abnormality that may interfere with the interpretation of study results and in the judgement of the investigator would make the subject unsuitable for entry into the study. * The subject is unwilling or unable to provide signed informed consent.