The purpose of this investigator-initiated trial is to evaluate whether the novel graft can prevent/reduce the disadvantages of the previously used replacement materials and shows better results than the group of patients, which were not operated. Since there is currently no alternative made of biological material to this product, this investigator-initiated trial is of great medical and economic importance. The otherwise following arthrosis or knee prosthesis implantation (TKA ) could be prevented or at least postponed. Initial clinical results are promising. An important and sensitive parameter for assessing the postoperative function of the meniscus is the MRI image. Genovese et al. 2007 were able to show in a categorization/classification which magnetic resonance image can be expected in the case of successful incorporation. Several studies have shown that the known clinical knee scores (Lysholm, IKDC, KOOS, VAS pain) improve significantly after successful ingrowth of the meniscus implant.
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To evaluate efficacy of the procedure using the KOOS Score
Timeframe: at 6 weeks, 6 and 12 months (operated patients) and at 2 years and 5 years
To evaluate efficacy of the procedure using the IKDC
Timeframe: at 6 weeks, 6 and 12 months (operated patients) and at 2 years and 5 years
To evaluate efficacy of the procedure using the VAS pain Score
Timeframe: at 6 weeks, 6 and 12 months (operated patients) and at 2 years and 5 years
Clemens Kösters, PD, Dr. med.