Associations Between Dietary Intake and Cardiometabolic and Gut Microbiota Outcomes (NCT06775132) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Associations Between Dietary Intake and Cardiometabolic and Gut Microbiota Outcomes
Singapore240 participantsStarted 2025-02-03
Plain-language summary
This cross-sectional study aims to investigate the associations between dietary intake, cardiometabolic health markers, and gut microbiota composition in Singapore adults.
Who can participate
Age range
21 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Able to give informed consent
. Adults 21-80 years old
. English-literate
. Have venous access sufficient to allow for blood sampling as per the protocol
. No drastic change of diet for the past 1 year
. If taking medication, has been consistently taking antihypertensive/cholesterol-lowering/type-2 diabetic medication for more than 5 years prior to starting the study.
Exclusion criteria
. Taking dietary supplements and fermented foods, which may impact the gut microbiota (e.g. antibiotics, prebiotics, probiotics, yogurt, kimchi) 2 months before starting the 1st study visit only.
. Taking dietary supplements or medications, which may impact sleep outcomes (e.g. Nutritional Shakes (e.g. Ensure), tryptophan, 5-hydroxytryptophan or melatonin supplementations) 1 month before starting the study.
. Taking dietary supplements which may impact the eye outcomes (e.g. Vitamin A, vitamin A-containing multivitamin) 2 months before starting the study.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This study is observational and actively collecting data on things like blood pressure, blood lipids, fasting glucose, and gut microbiota markers — does it involve any experimental treatments, or would I just be providing diet information and biological samples, and how might that fit into my current care?
2The trial is measuring gut health markers like short-chain fatty acids, TMAO, bile acids, and zonulin — could participating in this kind of research actually give me useful information about my own gut health and cardiometabolic risk, or is the data only used for research purposes?
3Since the trial is no longer actively recruiting, is there any chance I could still be considered for enrollment, or are there similar observational studies looking at diet and cardiometabolic or gut microbiota outcomes that might still be open?
4This study is tracking a wide range of outcomes including skin condition, sleep quality, and cognitive ability alongside cardiometabolic markers — given my specific health situation, would the time and effort of participating in something this broad be worthwhile compared to focusing on my direct treatment plan?
5The trial measures Endothelial Progenitor Cell Count and estimated GFR alongside dietary intake — are these markers something my doctor is already monitoring for me, and could my existing test results contribute to or overlap with what this study is trying to learn?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.