By InvitationNot Applicable

Liver and Spleen Stiffness to Predict the Presence of Esaphageal Varices in Cirrhotic With Advanced HCC

Italy150 participantsStarted 2023-06-20

Plain-language summary

Elasto-HCC is a prospective, uncontrolled, multicenter observational study involving several hepatology centers in Italy. Patients with liver cirrhosis and advanced hepatocellular carcinoma (HCC) who will need to undergo systemic therapy will be enrolled. Patients in the first phase will undergo measurement of liver and spleen stiffness and upper endoscopic evaluation and will subsequently be followed for 12 months

Who can participate

Age range18 Years – 80 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Age \> 18 yrs; * Cirrhotic patients of any etiology with aHCC scheduled to receive any line of systemic treatment for HCC; * Patients are willing and able to give informed consent. Exclusion criteria: * Presence of splenic, mesenteric, or portal vein thrombosis. * Previous placement of TIPS at the time of informed consent.

What they're measuring

: to evaluate the accuracy of Liver and Spleen stiffness in predicting the presence of high-risk EV needing treatment (VNT) in cirrhotic patients with aHCC who undergo systemic therapy.

Timeframe: from 2023 to 2025

Trial details

NCT IDNCT06773260

SponsorAzienda Ospedaliero Universitaria Policlinico Modena

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-06-15

View on ClinicalTrials.gov More Hepatocellular Carcinoma trials