Various Procedural Treatment Options for Post-acne Atrophic Scars (NCT06770608) | Clinical Trial Compass
Not Yet RecruitingPhase 2
Various Procedural Treatment Options for Post-acne Atrophic Scars
Pakistan60 participantsStarted 2025-01
Plain-language summary
Post acne scars are formed as a result of very inflamed and nodulocystic acne. Most common type of acne scars are atrophic scars and they are further classified on the basis of depth and size of destruction into ice pick, boxcar and rolling scars. Evaulating the most efficacious, safe and affordable treatment option is the need of the hour. This study is going to compare the efficacy of microneedling with autologous platelet rich plasma verses microneedling with topical insulin in the treatment of post-acne atrophic scars as to find out the relatively more effective and safer treatment.
Who can participate
Age range
13 Years – 50 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age: 13-50 years
* Gender: both male and female
* Type of acne scar: Atrophic acne scar
* Patients not taking prior treatment in last 1-2 months
Exclusion Criteria:
* Pregnancy and lactating females
* Bleeding disorders
* Platelet count less than 100000
* Hypersensitivity to insulin, PRP
* Keloidal tendency
* Active herpes simples, warts and molluscum contagiosum
* Unrealistic expectations
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is comparing microneedling with platelet-rich plasma against microneedling with topical insulin for acne scars — can you explain what each of those approaches actually involves, and which one might make more sense for my specific type of scarring?
2Since this is a Phase 2 trial that hasn't started recruiting yet, what does that mean for how much is already known about the safety and effectiveness of using topical insulin on acne scars compared to the PRP approach?
3Given that the trial isn't recruiting yet, is there a realistic timeline for when it might open, and in the meantime would any currently available standard treatments for my atrophic scars be worth starting now rather than waiting?
4Platelet-rich plasma is drawn from my own blood — are there any health conditions I have or medications I take that could affect whether that would be safe or practical for me to do?
5How would you compare the potential benefits and unknowns of joining this trial versus just pursuing microneedling with PRP or another established scar treatment outside of a study setting?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
To compare the outcome of microneedling with autologous platelet rich plasma verses microneedling with topical insulin in the treatment of post-acne atrophic scars
Timeframe: Clinical assessment for efficacy will be done monthly for 6 months