The Comparison of Tunnel Morphology and Graft Healing in Anterior Cruciate Ligament Reconstructio… (NCT06769711) | Clinical Trial Compass
CompletedNot Applicable
The Comparison of Tunnel Morphology and Graft Healing in Anterior Cruciate Ligament Reconstructions Using Peroneus Longus And Hamstring Tendons
Turkey (Türkiye)54 participantsStarted 2025-01-01
Plain-language summary
1. Comparison of the grafts using Magnetic Resonance Imaging (MR) to determine whether their maturation and bone integration are different,
2. Comparison of the grafts using Computerized Tomography (CT) to determine whether their effects on the tunnels opened in cruciate ligament reconstruction surgeries are different,
3. In the event that graft healing and effects on the tunnels differ between grafts, determination of whether these differences are related to patient clinics,
Who can participate
Age range
18 Years – 45 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients aged between 18 and 45 years.
* BMI in the range of 18 to 28.
* Diagnosed with an anterior cruciate ligament (ACL) injury preoperatively confirmed by MRI.
* Patients for whom it is deemed appropriate to harvest ipsilateral hamstring tendons or Peroneus Longus tendon for use as a graft.
Exclusion Criteria:
* History of previous surgery on the affected knee or ankle.
* Presence of multiple ligament injuries in the affected knee.
* ACL injuries that occurred more than 12 months prior to surgery.
* Evidence of unstable meniscal injury on preoperative MRI that may alter the -postoperative rehabilitation protocol.
* Inability to obtain a graft diameter of at least 9 mm using the isolated graft.
* Presence of meniscal tears requiring repair.
* Presence of advanced chondral lesions requiring surgical intervention.
* Intraoperative detection of multiple ligament injuries.
* Requirement for additional surgical procedures that would alter the standard rehabilitation protocol.
* Occurrence of intraoperative surgical complications.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Graft Maturation Assessed by Signal-to-Noise Quotient (SNQ) on MRI
Timeframe: 1 year postoperatively.
2
Tendon-Bone Healing Assessed by MRI Grading System
Timeframe: 1 year postoperatively.
3
Change in Tunnel Volume Assessed by CT
Timeframe: Within 1 week post-surgery and at 1 year post-surgery.