Active — Not RecruitingNot Applicable

The Comparison of Tunnel Morphology and Graft Healing in Anterior Cruciate Ligament Reconstructions Using Peroneus Longus And Hamstring Tendons

Turkey (Türkiye)58 participantsStarted 2025-01-01

Plain-language summary

1. Comparison of the grafts using Magnetic Resonance Imaging (MR) to determine whether their maturation and bone integration are different, 2. Comparison of the grafts using Computerized Tomography (CT) to determine whether their effects on the tunnels opened in cruciate ligament reconstruction surgeries are different, 3. In the event that graft healing and effects on the tunnels differ between grafts, determination of whether these differences are related to patient clinics,

Who can participate

Age range18 Years – 45 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients aged between 18 and 45 years. * BMI in the range of 18 to 28. * Diagnosed with an anterior cruciate ligament (ACL) injury preoperatively confirmed by MRI. * Patients for whom it is deemed appropriate to harvest ipsilateral hamstring tendons or Peroneus Longus tendon for use as a graft. Exclusion Criteria: * History of previous surgery on the affected knee or ankle. * Presence of multiple ligament injuries in the affected knee. * ACL injuries that occurred more than 12 months prior to surgery. * Evidence of unstable meniscal injury on preoperative MRI that may alter the -postoperative rehabilitation protocol. * Inability to obtain a graft diameter of at least 9 mm using the isolated graft. * Presence of meniscal tears requiring repair. * Presence of advanced chondral lesions requiring surgical intervention. * Intraoperative detection of multiple ligament injuries. * Requirement for additional surgical procedures that would alter the standard rehabilitation protocol. * Occurrence of intraoperative surgical complications.

What they're measuring

Graft Maturation Assessed by Signal-to-Noise Quotient (SNQ) on MRI

Timeframe: 1 year postoperatively.

Tendon-Bone Healing Assessed by MRI Grading System

Timeframe: 1 year postoperatively.

Change in Tunnel Volume Assessed by CT

Timeframe: Within 1 week post-surgery and at 1 year post-surgery.

Trial details

NCT IDNCT06769711

SponsorKaradeniz Technical University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-06-01