The Accuracy of Targeted Lymph Node Dissection of Non-small Cell Lung Cancer Patients According t… (NCT06768853) | Clinical Trial Compass
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The Accuracy of Targeted Lymph Node Dissection of Non-small Cell Lung Cancer Patients According to Predictive Models
China60 participantsStarted 2025-01-01
Plain-language summary
Investigators combined the clinical and radiomics characteristics of resectable non-small cell lung cancer patients to construct an accurate model for preoperative prediction of mediastinal lymph node status. For the patients in the experimental group, lymph nodes will be dissected based on the predicted lymph node status by the model, while in the control group, the lymph nodes will be dissected according to the NCCN guidelines (2023). Investigators expect that performing lymph node dissection according to the predictive model can lead to better prognosis for patients.
Who can participate
Age range18 Years – 70 Years
SexALL
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Inclusion criteria
✓. Age range from 18 to 70 years old;
✓. Chest CT shows a single pulmonary nodule, which may be adenocarcinoma or squamous cell carcinoma;
✓. Chest CT shows multiple pulmonary nodules, but preoperative evaluation suggests that pulmonary nodules other than the main lesion are benign;
✓. Preoperative auxiliary examination evaluates the patient as clinically resectable lung adenocarcinoma or squamous cell carcinoma in stages I, II, or IIIA (UICC-TNM 9th edition);
✓. ECOG score 0-1;
✓. Preoperative lung function FEV1 ≥ 1.0L and actual/expected value ≥ 80%;
✓. No contraindications for surgery;
✓. Technically, lobectomy or segmental resection combined with lymph node dissection can be performed;
Exclusion criteria
✕. Chest CT suggests multiple primary lung cancer or metastatic cancer;
What they're measuring
1
Consistency rate between preoperative prediction results and postoperative pathological results