The current research project aims to assess the insulin resistance (less sensitivity), from measures of insulin and glucose in response to a standard oral intake of glucose (standardized oral glucose tolerance test). For this, we wish to test and validate the method of glucose labelled 13-C (stable isotope) breath test in comparison with standardized methods to measure glucose and insulin. Comparative methods that will be used are measures of glycemia from venous blood withdrawal and continuous glucose measurement in the skin tissue (external face of the arm) using the Abbott's freestyle libre system. Repeatability and reliability of the 13-C glucose breath test will be checked from repeated measures over time.
Age range
18 Years – 40 Years
Sex
MALE
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1) To assess the within-subjects variability and overall repeatability of the 13C-glucose breath test
Timeframe: 0 to 300 minutes, after oral administration