LIFT-UP: Randomized Controlled Trial of Fortification of Human Milk

Inclusion Criteria: * Very LBW (≤1.5kg)\* or very preterm (≤32 weeks) infants admitted to NICU at study facility within 24 hours of birth for in-born infants and up to 48 hours for out-born\*\* * Mother and infant alive during screening * Mother age 18+ years * Lives within catchment areas of the facility * Mother intends to stay in catchment area of the study facility for at least 3 months * At randomization: Infant receiving at least 60 mL/kg/day of human milk\*\*\* Exclusion Criteria: * Lives outside the defined catchment area * Congenital abnormalities or acquired conditions that interfere with feeding or placement of nasogastric/orogastric tube \[cleft lip/palate, toxoplasmosis, other agents, rubella, cytomegalovirus, and herpes (TORCH), Trisomy 21, congenital cardiac defect, neural tube defect, gastrointestinal tract anomalies, hydrocephalus, NEC\] * Severe birth asphyxia * Critically ill (i.e. not on enteral feeds) * Unknown date of birth and unknown gestational age