Microbiome Changes After Laser and Chlorhexidine Disinfection in Caries Removal (NCT06765330) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Microbiome Changes After Laser and Chlorhexidine Disinfection in Caries Removal
Turkey (Türkiye)78 participantsStarted 2025-05-05
Plain-language summary
The aim of this study was to investigate the effects of cavity disinfection with laser and chlorhexidine on the microbiome in cavities prepared using different caries removal methods.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria:
* Permanent molar/premolar teeth in which the carious lesion is on the occlusal surface and extends to the middle third of the dentin at most
* Individuals with good oral hygiene
* Absence of clinical symptoms of periapical pathology
* Teeth in occlusion with the opposite tooth
* Individuals born in 2007 and before (\>18 years)
* Those who signed the Informed Voluntary Consent Form/Written Consent Form
Exclusion criteria:
* Irregular attendance at dental check-ups
* Severe systemic disease, allergy, and saliva flow disorder
* Poor oral hygiene
* Advanced periodontal disease
* Presence of clinically detected pulpal/periapical pathology
* Devitalisation of teeth
* The individual was born after 2007 (\<18 years)
* Those who do not sign the Informed Voluntary Consent Form/Written Consent Form
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.