Comparison of LASER Therapy and Desensitizing Agents in Dentinal Hypersensitivity (NCT06759454) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Comparison of LASER Therapy and Desensitizing Agents in Dentinal Hypersensitivity
Pakistan172 participantsStarted 2025-06-30
Plain-language summary
This study evaluates the effectiveness of laser therapy versus desensitizing agents in reducing pain among participants with dentinal hypersensitivity conducted in Saidu College of Dentistry. Pain will be measured at baseline, immediately post-treatment, one week, and three months using the Visual Analog Scale (VAS)
Who can participate
Age range
18 Years – 50 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Participants aged 18-50 years with a preoperative VAS score of ≥2 for dentinal hypersensitivity.
* Participants with sensitivity due to gingival recession, cervical abrasion, or enamel erosion.
* Participants with good systemic health.
* Minimum of two hypersensitive teeth present in two different quadrants.
Exclusion Criteria:
* Teeth with caries, defective restorations, or cervical defects \> 2 mm (may affect sensitivity measurements).
* Periodontal surgery or deep periodontal pockets (\> 6 mm) within the past three months (potential influence on periodontal health and sensitivity).
* Participants using desensitizing toothpaste within the past three months (could interfere with study outcomes).
* Presence of gross oral pathology or systemic diseases (e.g., eating disorders, chronic diseases, uncontrolled metabolic conditions) (may alter oral health status).
* Pregnant or lactating women (hormonal changes can influence oral health).
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in pain intensity: Visual Analog Scale
Timeframe: Immediately post-treatment, one week, and three months