Not Yet RecruitingNot Applicable

Postoperative Pain in Photodynamic Therapy Using Curcumin As a Photosensitizer

Turkey (Türkiye)50 participantsStarted 2025-01

Plain-language summary

In endodontics, various irrigation solutions are used to achieve antibacterial efficacy within the root canal. The antibacterial effect of curcumin-containing root canal solutions, when combined with photodynamic therapy, has been demonstrated in several studies. However, no research has specifically examined their effect on postoperative pain. The aim of this study is to investigate the impact of using a curcumin solution in combination with photodynamic therapy as the final irrigation solution on postoperative pain.

Who can participate

Age range18 Years – 60 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * healthy patients with aged between 18-60. * Incisor, canine, and premolar teeth that had previously undergone root canal treatment * Incisor, canine, and premolar teeth with a diagnosis of chronic apical abscess or asymptomatic apical periodontitis * teeth with only 1 root canal * the patients had not used any antibiotics for 3 months before treatment Exclusion Criteria: * the presence of a root fracture * teeth with any swelling * ankyloses, * periodontal pockets deeper than 4 mm. * teeth which a rubber dam could not be performed * patients with allergy to ibuprofen or ciprofloxacin were also excluded.

What they're measuring

postoperative pain levels

Timeframe: one week

Trial details

NCT IDNCT06752655

SponsorAtaturk University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-05

Contact for this trial

Meltem Sumbullu, DDS

+90 442 231 1111 meltem_endo@hotmail.com

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