CompletedNot Applicable

Rhomboid Intercostal and Subserratus Plane Block Versus Paravertebral Block for Thoracic Herpes Zoster

China30 participantsStarted 2024-01-01

Plain-language summary

Postherpetic neuralgia (PHN) is a common and debilitating complication of herpes zoster, characterized by persistent and severe pain. The rhomboid intercostal and subserratus plane (RISS) block, a novel ultrasound-guided regional anesthesia technique, has shown promise for various pain conditions, but its effectiveness for treating thoracic PHN remains relatively unexplored, and comparative studies against Paravertebral (PVB) block are lacking. This study aims to compare the efficacy and safety of RISS block versus PVB block for thoracic herpes zoster.

Who can participate

Age range44 Years – 82 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with typical manifestations of herpes zoster (HZ), such as vesicular and painful rash * herpes zoster neuralgia lasting more than one month and unresponsive to conventional treatment * a VAS score ≥ 4 * thoracic nerve root involvement Exclusion Criteria: * refused to provide written informed consent * unable to cooperate with assessments * history of systemic autoimmune disease, organ transplantation, or cancer * received other invasive treatments (e.g., spinal cord stimulation) * central nervous system disorder * coagulopathy * skin infection at the puncture site * pregnant/lactating

What they're measuring

Numerical Rating Scale(NRS)

Timeframe: At baseline (before therapy), on the day of treatment, at 7 days post-treatment, 30 days post-treatment, and 90 days post-treatment

Trial details

NCT IDNCT06751680

SponsorXiaguang Duan

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-01-12

View on ClinicalTrials.gov More Thoracic Herpes Zoster trials