RecruitingNot Applicable

Assessment of a Quantra-guided Transfusion Algorithm in Liver Transplantation

France56 participantsStarted 2025-03-08

Plain-language summary

Liver transplantation carries a substantial risk of bleeding, making precise haemostasis control essential, although assessing coagulation remains challenging. Quantra, a bedside viscoelastic testing device using sonorheometric methods, offers an innovative approach to guiding haemostatic management during surgery. The study aims to determine whether a Quantra-guided transfusion can reduce transfusion and bleeding during liver transplantation when compared to a conventional transfusion approach.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients aged 18 years or older * Patient with ESLD undergoing liver transplantation * Individuals affiliated with or beneficiaries of a social security scheme * Free and informed written consent obtained in writing from the patient, or where applicable from the trusted person/family member/close relative Non-inclusion Criteria: * Multi-organ transplantation * Congenital haemostasis disorder (such as haemophilia) * Patient under juridical protection (persons deprived of liberty or under curatorship or guardianship or safeguard of justice) * Pregnant or breast-feeding woman * Patient already enrolled in another interventional study with primary or secondary objective of reducing perioperative bleeding or transfusion

What they're measuring

Fresh Frozen Plasma (FFP) transfusion during liver transplantation surgery

Timeframe: Conducted during surgery

Trial details

NCT IDNCT06749405

SponsorUniversity Hospital, Toulouse

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-03

Contact for this trial

Guillaume PORTA BONETE, Md

561323565 porta-bonete.g@chu-toulouse.fr