Deep Learning Enhanced Detection of Aortic Stenosis - The DETECT-AS-Diagnostic Study (NCT06749145) | Clinical Trial Compass
By InvitationNot Applicable
Deep Learning Enhanced Detection of Aortic Stenosis - The DETECT-AS-Diagnostic Study
United States410 participantsStarted 2025-09-16
Plain-language summary
The DETECT-AS Diagnostic Study will assess the performance of artificial intelligence (AI) risk predictions to detect aortic stenosis using results from portable electrocardiogram (ECG) and cardiac ultrasound devices.
Who can participate
Age range
70 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Age 70 years or older
* Attending a routine outpatient primary care clinic at one of the three enrollment sites
Exclusion Criteria:
* Opted out of research studies
* Non-English speaking
* Urgent or emergent visits, defined as a visit for an illness or injury that needs attention quickly or is life-threatening
* Any echocardiogram within 12 months of clinic visit
* Prior history of moderate or severe AS
* Prior history of aortic valve replacement or repair, including transcatheter and surgical AVR with either a bioprosthetic or mechanical valve
* Presence of implantable cardiac devices, including permanent cardiac pacer, implantable cardioverter-defibrillator, or left ventricular assist device
* Prior heart transplant
* History of dementia
* Documented life expectancy of \<1 year or current participation in hospice services.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Number of participants diagnosed with advanced aortic stenosis (AS) by transthoracic echocardiogram (TTE)
Timeframe: Until 12 months from the baseline visit