By InvitationNot Applicable

IMAGINE: Pilot Trial of a Digital Group Intervention to Prevent Perinatal Depression

United States100 participantsStarted 2025-03-10

Plain-language summary

The goal of this clinical trial is to evaluate if a digital group intervention (named IMAGINE) can prevent depression in perinatal populations. The main questions it aims to answer are: Does IMAGINE engage cognitive behavioral therapy targets? Does IMAGINE lead to lower depression scores? Is IMAGINE acceptable, appropriate, usable and feasible? Participants will be randomized to either participate in an IMAGINE group for 12 weeks or receive standard of care. Participants will respond to questionnaires at enrollment and study visits at 12 and 24 weeks after enrollment.

Who can participate

Age range16 Years

SexFEMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Pregnant or up to 6 months postpartum * Age 16 or over * At elevated risk of perinatal depression (per USPSTF) * Speaks English or Spanish * PHQ9\<15 and no current major depression * Access to a smartphone with cellular data at least 3 days per week * If receiving other mental healthcare services, has been established in care at least 6 months and on stable treatment regimen Exclusion Criteria: none

What they're measuring

Depression symptoms

Timeframe: 24 weeks

Trial details

NCT IDNCT06746337

SponsorUniversity of Washington

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-10-31

View on ClinicalTrials.gov More Depression During Pregnancy trials