Confocal Laser Endomicroscopy Guided Cryobiopsy in the Diagnosis of Interstitial Lung Disease

Inclusion Criteria: * Patients with peripheral pulmonary nodules suspected of lung cancer by CT examination * Patients who intend to undergo a bronchoscopic lung biopsy to determine benign or malignant pulmonary nodules; * Age ≥18 years * Sign informed consent. Exclusion Criteria: * There is an uncorrectable coagulation disorder or anticoagulation therapy that cannot be stopped before surgery; * Tumors can be seen in the bronchus * Hemodynamic instability; * Refractory hypoxemia; * Patients with pregnant and lactating patients * Any illness or condition that interferes with the completion of the initial or subsequent assessment.