Scaling Up Community-based Noncommunicable Disease Research Into Practice in Pokhara Metropolitan… (NCT06740708) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Scaling Up Community-based Noncommunicable Disease Research Into Practice in Pokhara Metropolitan City of Nepal
Nepal2,100 participantsStarted 2025-04-28
Plain-language summary
The goal of this clinical trial is to evaluate whether a multifaceted community-based intervention, comprising 1) screening and lifestyle counseling by female community health volunteers (FCHVs); community health workers in Nepal, through home visits, and 2) regular Short Message Service (SMS) messages, can effectively reduce systolic blood pressure (SBP), lower fasting blood glucose, and increase smoking cessation rates among adults living in Pokhara with hypertension, type 2 diabetes, and smoking habits, respectively.
The main research questions are:
* Can FCHV home visits combined with regular mobile phone messages focused on blood pressure management reduce systolic blood pressure in adults with hypertension?
* Can FCHV home visits combined with regular mobile phone messages focused on diabetes management lower fasting blood glucose levels in adults with type 2 diabetes?
* Can FCHV home visits combined with regular mobile phone messages focused on smoking cessation increase the cessation rate among current smokers?
Researchers will compare the intervention group with a usual care group, which does not receive regular FCHV home visits for managing the three aforementioned risk factors or mobile phone messages.
Who can participate
Age range
40 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Meeting at least one of the following three conditions
. Registered on the voter list in Pokhara.
. Not planning to migrate outside of Pokhara during the study period
Exclusion criteria
. Blood pressure ≥180/120 mmHg or
. Blood glucose \>250 mg/dL or \<54 mg/dL
. Diagnosed with secondary hypertension by health professionals
. Diagnosed with other diabetes besides type 2 by health professionals
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is focused on community-based care in Pokhara, Nepal — given where I live and receive my care, is this study actually accessible or relevant to my situation?
2The trial is measuring systolic blood pressure, fasting plasma glucose, and smoking cessation together — if I only have one of these conditions, like hypertension or type 2 diabetes, does it still make sense to consider a study designed around all three?
3Since this trial is listed as 'active but no longer recruiting,' does that mean there's no possibility of joining, and if so, are there similar community-based programs or trials you'd recommend I look into instead?
4This is listed as a Phase NA study, which often means it's testing how to deliver care in real-world community settings rather than a new drug or device — can you help me understand what kind of intervention or support I'd actually be receiving if I were part of something like this?
5Given that standard treatments already exist for hypertension and type 2 diabetes, how would you weigh the potential benefit of a community-based research program like this against simply optimizing the treatment plan I'm already on?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Systolic blood pressure (mmHg)
Timeframe: 6 months post randomization
2
Fasting Plasma glucose
Timeframe: 6 months post randomization
3
Participants Who Have Achieved Smoking cessation
Timeframe: 6 months post randomization
Trial details
NCT IDNCT06740708
SponsorJohns Hopkins Bloomberg School of Public Health