RecruitingNot Applicable

Genetic Determinants of Exercise-Induced Muscle Damage (POLYGENDOMUS)

France300 participantsStarted 2023-03-13

Plain-language summary

The objective of this study is to evaluate the association between the evolution of plasma CPK levels and genetic polymorphisms, both before the muscle-damaging exercise and at three post-exercise time points. The investigators aim to include 300 participants in this research.

Who can participate

Age range18 Years – 35 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Male or female * Aged between 18 and 35 * Weighing more than 50 kg * Member of a sports club affiliated to an Olympic federation * Socially insured * Willing to comply with all study procedures and duration of the study Exclusion Criteria: * Medical history contraindicating sporting activities * Current medical treatment * Not a member of a sports club affiliated to an Olympic federation * Administrative reasons: impossibility of receiving informed information, impossibility of participating in the entire study, absence of social security coverage, refusal to sign consent form.

What they're measuring

The association between single nucleotide polymorphisms and exercise induced blood creatine kinase variation

Timeframe: Evolution of kinetics from Day 0 to Day 3 post experiment

Trial details

NCT IDNCT06740136

SponsorLille University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-06-28

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