RecruitingPhase 2

Effect of Superior Laryngeal Nerve Blocks on Patient Outcomes in Laryngeal Surgery

United States28 participantsStarted 2025-07-11

Plain-language summary

Patients undergoing surgery on their vocal cord will either receive a numbing injection to their throat or a saline injection during surgery. Symptoms such as how much coughing or pain patients have after surgery, as well as whether patient's voice gets better will be interrogated.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patient is aged 18 years or older at time of consent * Patient has suspected or confirmed benign vocal fold lesion * Patient is planning to undergo direct laryngoscopy with excision of the vocal fold lesion * Patient is English or Spanish speaking * Patient is not pregnant per self report * Patient is not incarcerated Exclusion Criteria: * Patient is not 18 years of age or older at consent date * Patient does not speak English or Spanish * Patient is currently pregnant or plans to become pregnant prior to their study procedure * Patient has a laryngeal malignancy or found to find a laryngeal malignancy on final pathology * Patient will not be undergoing direct laryngoscopy with excision of lesion * Patient is unable to provide consent or complete study activities * Patient is incarcerated

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Postoperative pain

Timeframe: 1, 3 and 7 days after surgery

Postoperative cough

Timeframe: Follow up appointment 2-4 weeks after surgery

Postoperative voice outcome

Timeframe: Postoperative appointment 2-4 weeks after surgery

Trial details

NCT IDNCT06734975

SponsorRutgers, The State University of New Jersey

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-12

Contact for this trial

Emma Thompson, MD

973-972-2548 ert46@njms.rutgers.edu

View on ClinicalTrials.gov More Vocal Cord Disease trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.