TerminatedNot Applicable

Arterial Stiffness for Improved Prediction of Coronary Artery Disease by Coronary CT Angiography

Stopped: Due to slow recruitment and lack of research staff at Danderyd University Hospital.

Sweden156 participantsStarted 2023-10-24

Plain-language summary

This study will evaluate the ability of device-estimated pulse wave velocity and machine learning methods to improve the prediction of potential symptomatic coronary artery disease

Who can participate

Age range30 Years – 70 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients undergoing coronary computer tomography angiography to investigate stable suspected symptomatic coronary artery disease. * Age 30 to \<70 years of age. Exclusion Criteria: * Known coronary artery disease (prior myocardial infarction, percutaneous coronary intervention, coronary artery bypass graft or any angiographic evidence of coronary artery disease ≥50% lesion in a major epicardial vessel). * Known significant cardiac (\> moderate valvular disease, heart failure with reduced ejection fraction, hypertrophic cardiomyopathy, or congenital heart disease), or pulmonary condition which could explain symptoms. * Known ongoing atrial fibrillation/flutter. * No Swedish social security number. * Unable to provide written informed consent.

What they're measuring

Improved area under receiver operating curve (ROC) to predict CAD-RADS ≥3

Timeframe: Typically within 1 month of enrollment

Trial details

NCT IDNCT06734247

SponsorDanderyd Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-07-01

View on ClinicalTrials.gov More Coronary Artery Disease trials