RecruitingNot Applicable

Pleural Irrigation With a Novel Devise.

United States10 participantsStarted 2025-05-25

Plain-language summary

Single-arm pilot trial of the use of intrapleural saline irrigation to treat retained pleural infections for patients with contraindications to standard of care intrapleural enzymatic therapy.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Retained pleural effusion identified via bedside ultrasound within the first 24 hours after chest tube insertion * Patient is contraindicated from receiving intrapleural enzymatic therapy within the first 24 hours after chest tube insertion Exclusion Criteria: * Non-infectious cause of pleural fluid analysis findings listed above identified (e.g. malignancy) * Post-procedural empyema or complicated parapneumonic effusion

What they're measuring

Radiographic improvement (reduction in the ammount of pleural effusion messured in centimeters) by bed side ultrasound day 1,2,3,4,5.

Timeframe: Daily for 8 days

Trial details

NCT IDNCT06727578

SponsorBeth Israel Deaconess Medical Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-05-25

Contact for this trial

Christine Conley

617-632-8386 Cconley@bidmc.harvard.edu

View on ClinicalTrials.gov More Pleural Effusion Disorder trials