Multiomics Study of Biological Behavior of Lymph Node Metastasis in Papillary Thyroid Carcinoma (NCT06725628) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Multiomics Study of Biological Behavior of Lymph Node Metastasis in Papillary Thyroid Carcinoma
2,000 participantsStarted 2024-12-01
Plain-language summary
Establish a predictive model for assessing neck lymph node metastasis of papillary thyroid carcinoma based on metabolomics, proteomics, and imaging omics data, exploring an ideal protocal for the precise diagnosis and treatment of papillary thyroid carcinoma."
Who can participate
Age range
18 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Pathological confirmation of PTC.
. Patients who underwent primary surgery accompanied by central neck lymph node dissection.
. Tumors measuring less than 2 cm in diameter.
. Postoperative pathological reports including detailed information on the number of lymph nodes dissected and the number of metastatic lymph nodes.
. Availability of comprehensive preoperative thyroid ultrasound images for analysis.
Exclusion criteria
. Postoperative pathological diagnosis indicating sub-types of PTC.
. Tumor invasion into adjacent anatomic structures such as the sternothyroid muscle, surrounding soft tissues, trachea, esophagus, or laryngeal nerve.
. History of neck trauma, previous tumor surgery, or adjuvant chemoradiotherapy.
. Fewer than three lymph nodes dissected during surgery.
. Concurrent acute inflammatory conditions or other hematologic disorders.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Lymph node metastasis status
Timeframe: Record lymph node metastasis status until the end of the surgery, followed by a one-year follow-up until the conclusion of the study.