Not Yet RecruitingNot Applicable

Multiomics Study of Biological Behavior of Lymph Node Metastasis in Papillary Thyroid Carcinoma

2,000 participantsStarted 2024-12-01

Plain-language summary

Establish a predictive model for assessing neck lymph node metastasis of papillary thyroid carcinoma based on metabolomics, proteomics, and imaging omics data, exploring an ideal protocal for the precise diagnosis and treatment of papillary thyroid carcinoma."

Who can participate

Age range18 Years – 80 Years

SexALL

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Inclusion criteria

✓. Pathological confirmation of PTC.
✓. Patients who underwent primary surgery accompanied by central neck lymph node dissection.
✓. Tumors measuring less than 2 cm in diameter.
✓. Postoperative pathological reports including detailed information on the number of lymph nodes dissected and the number of metastatic lymph nodes.
✓. Availability of comprehensive preoperative thyroid ultrasound images for analysis.

Exclusion criteria

✕. Postoperative pathological diagnosis indicating sub-types of PTC.
✕. Tumor invasion into adjacent anatomic structures such as the sternothyroid muscle, surrounding soft tissues, trachea, esophagus, or laryngeal nerve.
✕. History of neck trauma, previous tumor surgery, or adjuvant chemoradiotherapy.
✕. Fewer than three lymph nodes dissected during surgery.
✕. Concurrent acute inflammatory conditions or other hematologic disorders.

What they're measuring

Lymph node metastasis status

Timeframe: Record lymph node metastasis status until the end of the surgery, followed by a one-year follow-up until the conclusion of the study.

Trial details

NCT IDNCT06725628

SponsorTianhan Zhou

Sponsor typeOTHER_GOV

Study typeOBSERVATIONAL

Primary completion2024-12-01

Contact for this trial

Tianhan Zhou

8615556960687 201911122511374@zcmu.edu.cn

View on ClinicalTrials.gov More Papillary Thyroid Carcinoma trials