Not Yet RecruitingNot Applicable

VR and Scrip Training of PWA, Randomized Controlled Trial

105 participantsStarted 2025-06

Plain-language summary

The goal of this RCT is to investigate if computerized script training may promote functional communication and nonverbal cognitive functions of Cantonese-speaking PWA, and whether VR may further magnify the treatment outcomes. The main research questions are: 1. Can script training promote verbal functional communication of Cantonese-speaking PWA? 2. Can script training enhance nonverbal cognitive functions of Cantonese-speaking PWA? 3. Can VR magnify verbal and nonverbal treatment outcomes of script training of PWA?

Who can participate

Age range30 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. a stroke onset more than six months, with an Aphasia Quotient (AQ) below 96.4, as evaluated by the Cantonese version of Western Aphasia Battery (CAB; Yiu, 1992),
✓. premorbid fluent Cantonese speakers,
✓. aged between 30 and 80 years,
✓. no reported progressive neurogenic disorders such as dementia or Parkinson's disease,
✓. no motor speech disorders of moderate to severe level, and
✓. normal or corrected-to-normal vision and hearing functions

Exclusion criteria

✕. concurrent participation in other aphasia treatment trials, and
✕. incompatibility with immersive VR exposure such as complains of nausea, headache, or other severe discomforts during trial use of a head-mounted device during screening.

What they're measuring

Percentage accuracy of treatment probe correctly produced

Timeframe: From baseline up to 8-week post training

Time to produce each of the scripts in the treatment probe

Timeframe: From baseline up to 8-week post training

Number of sessions to reach performance criteria in session probe

Timeframe: From baseline up to 8-week post training

Trial details

NCT IDNCT06722092

SponsorThe Hong Kong Polytechnic University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-12

Contact for this trial

Winsy WS Wong, PhD

852-34003117 wszewong@polyu.edu.hk

View on ClinicalTrials.gov More Aphasia, Acquired trials

Plain-language summary

Who can participate

Age range30 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. a stroke onset more than six months, with an Aphasia Quotient (AQ) below 96.4, as evaluated by the Cantonese version of Western Aphasia Battery (CAB; Yiu, 1992),
✓. premorbid fluent Cantonese speakers,
✓. aged between 30 and 80 years,
✓. no reported progressive neurogenic disorders such as dementia or Parkinson's disease,
✓. no motor speech disorders of moderate to severe level, and
✓. normal or corrected-to-normal vision and hearing functions

Exclusion criteria

✕. concurrent participation in other aphasia treatment trials, and
✕. incompatibility with immersive VR exposure such as complains of nausea, headache, or other severe discomforts during trial use of a head-mounted device during screening.

What they're measuring

Percentage accuracy of treatment probe correctly produced

Timeframe: From baseline up to 8-week post training

Time to produce each of the scripts in the treatment probe

Timeframe: From baseline up to 8-week post training

Number of sessions to reach performance criteria in session probe

Timeframe: From baseline up to 8-week post training