VR and Scrip Training of PWA, Randomized Controlled Trial (NCT06722092) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
VR and Scrip Training of PWA, Randomized Controlled Trial
105 participantsStarted 2025-06
Plain-language summary
The goal of this RCT is to investigate if computerized script training may promote functional communication and nonverbal cognitive functions of Cantonese-speaking PWA, and whether VR may further magnify the treatment outcomes.
The main research questions are:
1. Can script training promote verbal functional communication of Cantonese-speaking PWA?
2. Can script training enhance nonverbal cognitive functions of Cantonese-speaking PWA?
3. Can VR magnify verbal and nonverbal treatment outcomes of script training of PWA?
Who can participate
Age range
30 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. a stroke onset more than six months, with an Aphasia Quotient (AQ) below 96.4, as evaluated by the Cantonese version of Western Aphasia Battery (CAB; Yiu, 1992),
. premorbid fluent Cantonese speakers,
. aged between 30 and 80 years,
. no reported progressive neurogenic disorders such as dementia or Parkinson's disease,
. no motor speech disorders of moderate to severe level, and
. normal or corrected-to-normal vision and hearing functions
Exclusion criteria
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Percentage accuracy of treatment probe correctly produced
Timeframe: From baseline up to 8-week post training
2
Time to produce each of the scripts in the treatment probe
Timeframe: From baseline up to 8-week post training
3
Number of sessions to reach performance criteria in session probe
Timeframe: From baseline up to 8-week post training
. concurrent participation in other aphasia treatment trials, and
. incompatibility with immersive VR exposure such as complains of nausea, headache, or other severe discomforts during trial use of a head-mounted device during screening.