RecruitingNot Applicable

MRgLITT for mTLE: A PROBE Trial

China120 participantsStarted 2025-07-21

Plain-language summary

How does magnetic resonance-guided laser interstitial thermal therapy (MRgLITT) impact clinical prognosis in mesial temporal lobe epilepsy (mTLE)?

Who can participate

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 18-65 years. * Drug-resistant mesial temporal lobe epilepsy. * Seizure frequency ≥ 1 time /month. * Participants approved. Exclusion Criteria: * History of brain surgery. * Intracranial space occupying lesions. * Individuals with significant medical comorbidities or conditions that pose an excessive risk for surgery, such as severe cardiovascular disease, respiratory disorders, or uncontrolled systemic infections.

What they're measuring

Seizure freedom rate

Timeframe: 6-month, 1-year after surgery

Trial details

NCT IDNCT06720922

SponsorBeijing Tiantan Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-01-01

Contact for this trial

Kai Zhang, Dr.

86 01059975051 zhangkai62035@sina.com

View on ClinicalTrials.gov More Temporal Lobe Epilepsy (TLE) trials