Tranexamic Acid Therapy For The Treatment of Subdural Hematomas

Inclusion Criteria: * CT scan demonstrating existence of a subdural hematoma, unilateral or bilateral, containing a chronic component * Neurosurgeon evaluation deemed patient to not need surgery * Diagnosis within the last 14 days * Signed informed consent * Competence to take study medications properly and regularly or access to care giver that is able to comply with accurate study medication administration Exclusion Criteria: * Planned surgery, burr-hole craniostomy or mini-craniotomy for their chronic subdural hematoma based on one or more of the following symptoms: medically intractable headache, midline shift \>5mm, SDH thickness \>10mm, increased ICP, imminent death within 24 hours * Structural causes for subdural hemorrhage (arachnoid cysts, cortical vascular malformations) * Recent ischemic stroke * Other concomitant intracranial pathology (intracranial malignancy) * Active malignancy * Need for chronic therapeutic anticoagulation (i.e. atrial fibrillation) * Acute subdural hematoma with no chronic component * Active treatment for deep vein thrombosis, pulmonary embolism or cerebral thrombosis (secondary prophylaxis is not considered to be active treatment) * Known hereditary thrombophilia, including Factor V Leiden, Antithrombin III mutation, Protein C deficiency, Protein S deficiency * History of thrombosis or thromboembolism, including retinal vein or artery occlusions * An intrinsic risk of thrombosis or thromboembolism * Aneurysmal subarachnoid hemorrhage * Co…