This study investigates the potential for temporally-interfering electric field stimulation (TIEFS) to treat epilepsy. In this case series within and between subjects design, the impact of TIEFS on epilepsy biomarkers was studied in patients with medial temporal lobe epilepsy. Secondary analyses examine the underlying physiological effects of TIEF on local brain activity and brain networks.
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Reduction of Interictal Biomarkers of Epilepsy
Timeframe: From enrollment until the end of the admission for each patient (the admission is typically 7-14 days in duration).