A Study on Different Treatments for Knee Osteoarthritis Caused by Damaged Roots of the Medial Men⦠(NCT06707948) | Clinical Trial Compass
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A Study on Different Treatments for Knee Osteoarthritis Caused by Damaged Roots of the Medial Meniscus.
69 participantsStarted 2024-11-30
Plain-language summary
Medial meniscus posterior root tears (MMPRT) account for 20% or more of all meniscus tears, but the diagnosis and treatment of this condition continues to plague the general population due to the complexity of the diagnosis and uncertainty of the treatment. Early as well as timely diagnosis and treatment is one of the effective ways to avoid accelerated knee degeneration. Based on this study, our team is going to conduct a clinical study on posterior medial meniscus tear, combining Magnetic Resonance Imaging(MRI) to dynamically assess the changes of meniscus and articular cartilage surface after the injury, and selecting a specific patient group to carry out different therapeutic interventions, which mainly include conservative treatment, partial meniscectomy, and meniscal repair, in order to clarify the effects of different treatment modalities on the articular cartilage after the posterior meniscus tear, and to help to delay the degeneration of knee joints. This is to clarify the effects of different treatment modalities on the articular cartilage after posterior medial meniscus tears and to provide appropriate advice for delaying the progression of osteoarthritis of the knee.
Who can participate
Age range50 Years β 65 Years
SexALL
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Inclusion criteria
β. Clinical diagnosis of posterior root tear of the medial meniscus;
β. Patients with K-L classification β€ grade II;
β. The age range of 50-65 years old;
β. International Cartilage Repair Society (ICRS) Modified Magnetic Resonance Imaging Grading System β€ Grade 2;
β. International Cartilage Repair Society (ICRS) arthroscopic grading system β€ grade 2;
β. Knee joint mobility β₯90Β°;
β. Inversion deformity β€10Β°;
β. Must be able to complete follow-up MRI within 2 years after knee meniscus surgery;
Exclusion criteria
β. Can not participate in this study;
β. Patients with concomitant meniscal injuries elsewhere;
β
What they're measuring
1
the incidence of KOA
Timeframe: 30th November 2024 -30th November 2027
Trial details
NCT IDNCT06707948
SponsorShanghai General Hospital, Shanghai Jiao Tong University School of Medicine