RecruitingNot Applicable

NSCLC Liquid Biopsies and Exhaled VOC

Canada210 participantsStarted 2023-02-01

Plain-language summary

The objective of the study is to determine the feasibility of recruiting participants and using sputum, Bronchoalveolar lavage (BAL) and exhaled Volatile Organic Compounds (VOC) in addition to blood, as biological samples for detecting mutations in extracted cell-free DNA in non-small cell lung cancer (NSCLC) patients, before and after surgery, and any recurrence within a 24-month postoperative follow-up period. This is a pilot feasibility study, proposed as a 24-month prospective, single-center, non-interventional, observational trial with NSCLC-adenocarcinoma patients indicated for resection surgery with curative intent.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patient must be at least 18 years of age * Patient must be able to provide consent * Patients undergoing surgical resection with curative intent for non-small cell lung cancer at St. Joseph's Healthcare Hamilton and Firestone Institute for Respiratory Health. Exclusion Criteria: * Resection done with non-curative intent or metastatic disease * other malignancies * Patients with previously treated malignancy less than 5 years prior to current resection (not including skin cancer).

What they're measuring

Recruitment rate

Timeframe: December 2025

Data completion rate

Timeframe: December 2025

Safety, adverse events

Timeframe: December 2025

Trial details

NCT IDNCT06707519

SponsorSt. Joseph's Healthcare Hamilton

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2027-12-29

Contact for this trial

Layla Halwagi, BSc

905-522-1155 Lhalwagi@stjosham.on.ca

View on ClinicalTrials.gov More Lung Cancer trials