Not Yet RecruitingNot Applicable

Protective Effect of RIPC Against Negative Inflammatory Response and Organ Dysfunction After Cardiovascular Surgery (Panda VII)

China500 participantsStarted 2024-12-01

Plain-language summary

Remote ischaemic pre-conditioning (RIPC) has been recognized as a low-cost, non-invasive intervention method by applying brief ischaemia and reperfusion on an arm or a leg. Previous studies have mainly focused on the organoprotective effects of RIPC in patients undergoing cardiac surgery. However, whether it has an organ-protecting effect is still highly debated. We aimed to determine whether intensive RIPC can prevent from negative inflammatory response and organ dysfunction as well as postoperative complications in patients undergoing cardiovascular surgery.

Who can participate

Age range18 Years – 80 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * patients at high risk for organ dysfunctions who underwent elective cardiovascular surgery requiring cardiopulmonary bypass (CPB); * age of 18 -80 years old, regardless of gender; * subjects voluntarily participate in the trialand sign the informed consent; Exclusion Criteria: * 1\) Arm fracture, skin injury or infection; * 2\) There is limb nerve injury; * 3\) Limb placement PICC, arteriovenous fistula and other devices that affect armband placement; * 4\) There are basic vascular lesions and poor blood supply at the extremities; * 5\) Limb thrombosis.

What they're measuring

∆SOFA

Timeframe: within the prior 7 days after cardiac surgery.

Trial details

NCT IDNCT06707350

SponsorNanjing Medical University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-12-31

Contact for this trial

Hong Liu, MD

18801281613 dr.hongliu@foxmail.com

View on ClinicalTrials.gov More Cardiopulmonary Bypass trials