Effect of Topical Active Oxygen Therapy on Surgical Site Wound Healing and Microbial Colonization (NCT06705920) | Clinical Trial Compass
Active — Not RecruitingEarly Phase 1
Effect of Topical Active Oxygen Therapy on Surgical Site Wound Healing and Microbial Colonization
Egypt44 participantsStarted 2024-11-01
Plain-language summary
To assess the antibacterial efficiency of oxygenated gel therapy on wound healing and microbiological colonization around surgical sutures
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Adult patients in a healthy systemic condition who required comprehensive dental treatment
* Both genders with age group \> 18 years old
* Patients should approve to deliver a signature to a written consent after study nature explanation.
Exclusion Criteria:
* Patients with severe smoking habits \>10 cig \\ day
* Pregnant females, decisional impaired individuals and handicapped patients
* Patients having poor oral hygiene or not wanting to carry out oral hygiene measures
* Patients on any medication affecting the soft tissue health (e.g., amlodipine, Cyclosporine A, hydantoin)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is in Early Phase 1, which means it's still at a very early stage of testing — what does that mean for how much is already known about whether topical active oxygen therapy is safe to use on oral surgical wounds?
2Since the trial is 'active but not recruiting,' it's already underway with other participants — would it be possible to see any early findings or safety updates before deciding whether this kind of treatment is right for my situation?
3The study is looking at wound healing and bacterial levels after oral flap surgery that requires sutures — how does my specific planned procedure compare to the types of surgeries being studied, and would my wound be similar enough to make the results relevant to me?
4Given that this involves applying an oxygen-based therapy directly to a surgical site in the mouth, what are the potential risks or unknowns I should understand before considering anything like this?
5Are there standard wound care approaches already used after oral flap surgery that have a more established safety and effectiveness record, and how would those compare to what's being tested in this trial?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.