Assessing Cognitive Decline at Home (NCT06704971) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Assessing Cognitive Decline at Home
United States25 participantsStarted 2024-10-01
Plain-language summary
Neuropsychiatric symptoms (NPS) refer to a range of mental and emotional issues that can be observed through how patients move, perform daily tasks, and express feelings on their faces. In this study, the investigators want to find ways to accurately and unobtrusively track these symptoms in people's homes over time. Our goals are to note when these symptoms happen, predict potential problems, and gather clear data to help doctors make accurate diagnoses.
To do this, the investigators will first collect information from participants who have in-home sensors. the investigators will then use special computer programs that can recognize everyday activities and identify features that connect to scores from the Mild Behavioral Impairment Checklist (MBI-C). These scores will be compared to a questionnaire (NPIQ) filled out by caregivers or family members, along with any relevant information from doctors about the patients' symptoms. The investigators aim to see how these features can help differentiate between types of NPS, such as mood changes and agitation.
Finally, the investigators will create a dashboard for doctors that summarizes the patterns of these symptoms in patients, making it easier to monitor and manage their mental health.
Who can participate
Age range
65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria:
* Age 65+ years old
* Any age and ethnicity.
* With or without, or at risk of mild to moderate dementia and healthy controls.
* Availability of a study partner (informant) who has contact with the patient at least once a week (this can also be the surrogate/LAR but does not necessarily have to be)
Exclusion criteria:
* Those with severe mobility impairments
* participants in non-home settings (skilled nursing facilities, etc.).
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This study seems focused on tracking neuropsychiatric symptoms like mood and behavior changes at home — given my specific diagnosis, does the kind of data this trial collects actually align with what my care team most needs to monitor in my situation?
2Since this trial is listed as 'active but not recruiting,' is there any chance my doctor knows of a similar home-based cognitive monitoring study that is still enrolling, or a comparable tool we could use outside of a trial?
3The trial aims to build a personalized dashboard for clinicians to interpret neuropsychiatric symptoms — how would information like that actually change the way you manage my care compared to what we're already doing at regular appointments?
4Because this study is listed as Phase NA, which often means it's more about developing and testing a tool than proving a treatment works, what does that mean for what I'd actually get out of participating versus pursuing standard clinical monitoring?
5If a home-based symptom-tracking system like the one in this trial were available to me, what symptoms or behavioral changes would you most want it to capture, and are there already approved ways to do that monitoring now?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
develop a personalized and clinically interpretable NPS assessment system