Awake Transnasal Laser-assisted Surgery (TNLS) and Microlaryngeal Surgery for Vocal Cord Cyst (NCT06703515) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
Awake Transnasal Laser-assisted Surgery (TNLS) and Microlaryngeal Surgery for Vocal Cord Cyst
Hong Kong54 participantsStarted 2024-12-01
Plain-language summary
This is a prospective randomised controlled trial conducted at two tertiary referral hospitals in Hong Kong to compare the clinical and functional outcomes of office-based awake transnasal laser-assisted laryngeal surgery (TNLS) under local anesthesia to traditional microlaryngeal surgery for vocal cord cyst under general anesthesia.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients with vocal cord cysts
* older than 18-year-old
* able to independently provide consent
* able to tolerate flexible laryngoscopy would be recruited
Exclusion Criteria:
* under 18-year-old
* unable to independently give an informed consent
* unable to tolerate flexible laryngoscopy
* allergic to local anesthesia
* had unfavorable anatomy such as prolapsing epiglottis precluding adequate visualization, extensive lesions and an expected difficult operation as judged by the surgeons
* with pathologies other than vocal cord cyst
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial compares two surgical approaches for vocal cord cysts — awake transnasal laser surgery versus microlaryngeal surgery under general anesthesia — can you help me understand which approach might be more appropriate for my specific situation and why?
2Since this trial isn't recruiting yet, how soon do you think it might open, and should I consider starting standard treatment now rather than waiting to see if I qualify?
3The main thing being measured in this study is the Voice Handicap Index, which tracks how much my voice problem affects my daily life — based on my current symptoms, how meaningful do you think that kind of improvement would be for me personally?
4One of these procedures is done while I'm awake — how realistic is that for someone in my situation, and what should I know about what that experience actually involves before considering it?
5Are there currently accepted standard treatments for a vocal cord cyst that I should discuss as a first option, especially given that this trial hasn't started enrolling patients yet?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.