CompletedNot Applicable

Can Neutrophil-to-Lymphocyte Ratio, Platelet Volume and Platelet Distribution Width Be Used as Indicators of Delirium?

Turkey (Türkiye)221 participantsStarted 2022-11-14

Plain-language summary

Postoperative delirium is a frequent complication in children undergoing general anesthesia. It has been suggested that inflammation and oxidative stress contribute to the pathophysiology of delirium. The aim of this prospective observational study was to investigate the relationship between inflammatory markers, and delirium. The main questions it aimed to answer were: * Is there a realtionship between delirium and neutrophil-to-lymphocyte ratio? * Is there a realtionship between delirium and platelet volume? * Is there a realtionship between delirium and platelet distribution width? * What is the incidence of postoperative delirium in the study group?

Who can participate

Age range

3 Years – 9 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * ASA I-III risk group * Planned to have adenoidectomy, tonsillectomy, and/or ventilation tube placement. Exclusion Criteria: * Children under 3 years old * Children over 9 years old

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Neutrophil-to-lymphocyte ratio in the study group including patients with and without delirium

Timeframe: Preoperatively, at the preoperative assessment

Platelet volume in the study group including patients with and without delirium

Timeframe: Preoperatively, at the preoperative assessment

Platelet Distribution Width in the study group including patients with and without delirium

Timeframe: Preoperatively, at the preoperative assessment

Incidence of postoperative delirium

Timeframe: 30 minutes postoperatively

Trial details

NCT IDNCT06701643

SponsorAnkara City Hospital Bilkent

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-02-14

View on ClinicalTrials.gov More Delirium - Postoperative trials

Plain-language summary

Who can participate

Age range

3 Years – 9 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Neutrophil-to-lymphocyte ratio in the study group including patients with and without delirium

Timeframe: Preoperatively, at the preoperative assessment

Platelet volume in the study group including patients with and without delirium

Timeframe: Preoperatively, at the preoperative assessment

Platelet Distribution Width in the study group including patients with and without delirium

Timeframe: Preoperatively, at the preoperative assessment

Incidence of postoperative delirium

Timeframe: 30 minutes postoperatively