CompletedNot Applicable

Sweet Thresholds in Healthy Volunteers Study

United Kingdom30 participantsStarted 2024-11-27

Plain-language summary

The sweet threshold (concentration of sucrose in water) at which healthy participants can detect a sweet flavour will be recorded.

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: . Male and female adults of 18 years old and over; * Participants without a diagnosis of major depressive disorder (MDD) / anxiety disorder; * Participants not taking an antidepressant during the preceding 6 months * Not suffering from significant other mental or physical illness, such as confirmed psychosis, end of life care, or any other condition assessed as significant by the Site Investigator; * Willing and able to comply with all study-related procedures; * Not having COVID 19 or continuing effects of COVID 19 including altered sense of taste; * Understands the study requirements and the treatment procedures and is able to provide written informed consent. Exclusion Criteria: * Taking antidepressant medication currently or during the previous 6 months; * Known or suspected hypersensitivity or intolerance to any taste testing solutions, or any of their excipients; * A history or presence of neurological or confounding psychiatric conditions (such as stroke, traumatic brain injury, epilepsy, space occupying lesions, multiple sclerosis, Parkinson's disease, vascular dementia, transient ischemic attack, or schizophrenia); * Patients with a diagnosis of chronic pain; * Pregnancy or possibility pregnancy, or breastfeeding; * Participants using supplements containing psychoactive herbs (for example St Johns Wort or 5-HTP (5-Hydroxytryptophan, also known as oxitriptan); * Participants regularly using psychoactive stimulants (for example MDMA); * Particip…

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Sweet taste threshold

Timeframe: From enrolment to a final taste test 6 weeks later

Trial details

NCT IDNCT06697847

SponsorRanvier Health Ltd

Sponsor typeINDUSTRY

Study typeOBSERVATIONAL

Primary completion2025-01-31

View on ClinicalTrials.gov More Taste Thresholds in Healthy Volunteers trials

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.