Not Yet RecruitingNot Applicable

A Smartphone Application (QuitBot) for the Improvement of Smoking Cessation Among American Indians and Alaska Natives, NAITIVE Trial

United States772 participantsStarted 2026-06-01

Plain-language summary

This clinical trial develops a chatbot smartphone application (app), QuitBot, and text messaging to help American Indians (AI) and Alaska Natives (AN) to quit smoking commercial tobacco (smoking cessation), and evaluates two remote smoking cessation programs to see how well they work for helping AI/AN people quit smoking commercial tobacco. AI/AN populations have one of the highest rates of commercial cigarette smoking of any racial and ethnic group in the United States (US). They also have a higher rate of developing smoking-related cancer but are less likely to quit smoking. The two programs are designed to provide personalized support in setting a smoking cessation goal, tasks to reach the smoking cessation goal, and motivation to remain smoke-free. This may help to keep participants engaged and support them in their quit efforts, and may improve smoking cessation among AI and AN.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Self-identifying as American Indian or Alaska Native, either alone or in combination with other races * Age 18 and older * Smoking combustible cigarettes daily in the past year * Interest in quitting smoking * Interest in learning skills to quit smoking * Willing to be randomly assigned * Have daily access to their own Android or iPhone smartphone * Ability to download a smartphone app * Ability to read English * Not currently (i.e., within past 30 days) using other smoking cessation interventions * No prior participation in our studies * No prior use of SFT * No household or family member participating * US residency for the next twelve months * Willingness to complete follow-up assessments at the 3-, 6-, and 12-month follow-ups * Providing email, phone number(s), and mailing address Exclusion Criteria: * The reverse of the inclusion criteria * Pregnant or breastfeeding * Use of other tobacco products (e.g., ceremonial use of tobacco, e-cigarettes) will be assessed but is not an exclusion criterion, as it would limit the study's generalizability

What they're measuring

30-day point prevalence abstinence (PPA)

Timeframe: At 12-months post-randomization

Trial details

NCT IDNCT06697496

SponsorFred Hutchinson Cancer Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2029-10-31

Contact for this trial

Jonathan Bricker, PhD

206-667-5074 jbricker@fredhutch.org