A Smartphone Application (QuitBot) for the Improvement of Smoking Cessation Among American Indian… (NCT06697496) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
A Smartphone Application (QuitBot) for the Improvement of Smoking Cessation Among American Indians and Alaska Natives, NAITIVE Trial
United States772 participantsStarted 2026-09-30
Plain-language summary
This clinical trial develops a chatbot smartphone application (app), QuitBot, and text messaging to help American Indians (AI) and Alaska Natives (AN) to quit smoking commercial tobacco (smoking cessation), and evaluates two remote smoking cessation programs to see how well they work for helping AI/AN people quit smoking commercial tobacco. AI/AN populations have one of the highest rates of commercial cigarette smoking of any racial and ethnic group in the United States (US). They also have a higher rate of developing smoking-related cancer but are less likely to quit smoking. The two programs are designed to provide personalized support in setting a smoking cessation goal, tasks to reach the smoking cessation goal, and motivation to remain smoke-free. This may help to keep participants engaged and support them in their quit efforts, and may improve smoking cessation among AI and AN.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Self-identifying as American Indian or Alaska Native, either alone or in combination with other races
* Age 18 and older
* Smoking combustible cigarettes daily in the past year
* Interest in quitting smoking
* Interest in learning skills to quit smoking
* Willing to be randomly assigned
* Have daily access to their own Android or iPhone smartphone
* Ability to download a smartphone app
* Ability to read English
* Not currently (i.e., within past 30 days) using other smoking cessation interventions
* No prior participation in our studies
* No prior use of SFT
* No household or family member participating
* US residency for the next twelve months
* Willingness to complete follow-up assessments at the 3-, 6-, and 12-month follow-ups
* Providing email, phone number(s), and mailing address
Exclusion Criteria:
* The reverse of the inclusion criteria
* Pregnant or breastfeeding
* Use of other tobacco products (e.g., ceremonial use of tobacco, e-cigarettes) will be assessed but is not an exclusion criterion, as it would limit the study's generalizability
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial uses a smartphone app called QuitBot designed specifically for American Indians and Alaska Natives — do you think a culturally tailored digital tool like this could be a good fit for me compared to other quit-smoking programs you might recommend?
2Since this trial isn't recruiting yet, how long do you think it might be before enrollment opens, and should I be pursuing other smoking cessation options in the meantime rather than waiting?
3The trial is measuring whether people go 30 days without smoking as its main goal — is that kind of short-term abstinence a meaningful milestone for reducing my cancer-related risks, or would we need longer-term quitting to make a real difference?
4Because this trial is listed as Phase NA, meaning it may be more of a behavioral study than a drug trial, what does that mean for my safety, and are there any risks involved in participating that I should understand before considering it?
5Are there already proven smoking cessation treatments — like nicotine replacement therapy, prescription medications, or counseling programs — that you'd recommend I try first while this trial is still getting started?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.