CompletedNot Applicable

Benefits of Intrahospital Exercise Program in Pediatric HSCT

United States40 participantsStarted 2017-10-01

Plain-language summary

This randomized control study examines the effect of an intrahospital exercise regimen on the physical deconditioning that occurs due to hematopoietic stem cell transplant in the pediatric population.

Who can participate

Age range

4 Years – 21 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Patients ages 4-21 years of age who present for hematopoietic stem cell transplant.
. Karnofsky (if ≥16 years) or Lansky (if \<16 years) score \>60 at enrollment and prior to each testing point
. Parental/guardian permission (informed consent) and child assent prior to transplant.

Exclusion criteria

. Patients with any preexisting need for gait assistance such as crutches, wheelchair, braces, or walker
. Previous stem cell transplant in the last 6 months
. Patients with grade 3 or greater sensory/motor neuropathy

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change from Baseline 6-minute walk test at 6 weeks discharge.

Timeframe: Average of 100 days post-transplant

Change from Baseline Manual Muscle Testing at 6 weeks post discharge

Timeframe: Average of 100 days post-transplant

WeeFIM

Timeframe: Average of 100 days post-transplant

Trial details

NCT IDNCT06692478

SponsorPhoenix Children's Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2019-08-01

View on ClinicalTrials.gov More Hematopoietic Stem Cell Transplant trials

Who can participate

Age range

4 Years – 21 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Patients ages 4-21 years of age who present for hematopoietic stem cell transplant.
. Karnofsky (if ≥16 years) or Lansky (if \<16 years) score \>60 at enrollment and prior to each testing point
. Parental/guardian permission (informed consent) and child assent prior to transplant.

Exclusion criteria

. Patients with any preexisting need for gait assistance such as crutches, wheelchair, braces, or walker
. Previous stem cell transplant in the last 6 months
. Patients with grade 3 or greater sensory/motor neuropathy