Effectiveness of an Air Purifier on Asthmatic and Cat-allergic Subjects in the ALYATEC Environmen… (NCT06691568) | Clinical Trial Compass
CompletedNot Applicable
Effectiveness of an Air Purifier on Asthmatic and Cat-allergic Subjects in the ALYATEC Environmental Exposure Chamber
France30 participantsStarted 2023-01-20
Plain-language summary
The goal of this clinical trial is to evaluate the efficacy of air purifiers in reducing allergy symptoms in patients with a cat allergy. The main question it aims to answer is:
If there is a reduction of early asthmatic response (EAR) compared to placebo.
Participants were asked to remain in an exposure chamber for 2 hours while their symptoms were monitored.
Who can participate
Age range
18 Years – 65 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Subjects who signed the written informed consent
* Men or women aged between 18- and 65-year-old
* Subjects covered by health social identification number
* Subjects able to understand and complete study-related procedures
* Subjects reported history of symptomatic cat allergen-triggered asthma (GINA1-2) with or without associated allergic rhinitis and/or conjunctivitis
* Positive skin prick test (SPT) with cat hair extract with mean wheal diameter ≥ 5 mm compared to negative control (NaCl reaction \< 2 mm)
* Subjects with FEV1≥70% predicted at screening and before allergen exposure,
* Subjects with at least one drop in FEV1 ≥ 20% within the 2- hours exposure at baseline (V2)
* Women of childbearing potential with a negative pregnancy test throughout the study period and highly effective contraception: oral contraceptives, condom with spermicide, intrauterine device, bilateral tubal ligation, vasectomized partner.
Exclusion Criteria:
* Allergen immunotherapy to cat allergen for more than 1 month in the 3 years prior to the screening visit
* Ongoing allergen immunotherapy to another allergen
* History of anaphylactic reactions to cat allergen exposure or cat allergen immunotherapy
* History of anaphylactic reactions to another allergen in the last 6 weeks before inclusion
* Nasal polyposis, deviation of nasal septum, or diagnosis of uncontrolled non- allergic rhinitis
* Subjects allergic to indoor environmental allergens (molds, house dust mite allerge…
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
To measure the efficacy of air purifier on reducing the frequency of early asthmatic response (EAR) during a 2-hour cat allergen exposure in ALYATEC EEC compared to placebo.