Clinical Studies of the Efficacy and Safety of Remimazolam for Anesthesia Induction and Maintenan… (NCT06690424) | Clinical Trial Compass
CompletedPhase 4
Clinical Studies of the Efficacy and Safety of Remimazolam for Anesthesia Induction and Maintenance in Elderly Patients
China92 participantsStarted 2025-06-20
Plain-language summary
the investigators are conducting a clinical study on the efficacy and safety of remimazolam for induction and maintenance of anesthesia in elderly patients. Project number: CRCF-YXFN-202401029, funded by the Red Cross Foundation of China and will take more than 2 years to complete.
This is a single-center, randomized, controlled clinical study, randomized 60 elderly subjects undergoing general anesthesia for elective surgery. According to the random number method, propofol group (control group, group P) and remimazolam group (experimental group, group R), 30 cases in each group.
By participating in this study, it is possible to make anesthesia induction rapid and stable, stable intraoperative circulation, rapid recovery and safe and comfortable, reduce the Incidence of intraoperative awareness, arrhythmia, postoperative delusion, and so on, which is conducive to rapid postoperative recovery and reduce hospitalization costs.
Who can participate
Age range60 Years – 75 Years
SexALL
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Inclusion criteria
✓. Patients undergoing surgery for clinically diagnosed thyroid tumors
✓. Patients with general anesthesia
✓. Patients requiring endotracheal intubation
✓. American Society of Anesthesia gradeⅡ to grade Ⅲ
✓. age 60-75 years old
✓. body mass index was between 18 and 28
✓. Patients or their family was clear about the study process and volunteered to participate.
Exclusion criteria
✕. Patients with known allergy to remimazolam or with previous history of severe allergy and family history
✕. Patients with long-term use of narcotic analgesics, sedatives, or non- steroidal anti-inflammatory drugs
✕. Patients with drug taking, opioid dependence or tolerance
What they're measuring
1
Success rate of induction of anesthesia
Timeframe: At 5 minutes after the onset of anesthesia induction