Multisensory Integration and Cognitive Awareness in Post-Stroke Unilateral Spatial Neglect (NCT06690125) | Clinical Trial Compass
CompletedNot Applicable
Multisensory Integration and Cognitive Awareness in Post-Stroke Unilateral Spatial Neglect
Italy36 participantsStarted 2018-11-07
Plain-language summary
The primary aim of this study is to investigate whether multisensory integration (MSI) mechanisms observed in patients with right hemisphere lesions without neglect remain intact compared to patients with Unilateral Spatial Neglect (USN).
This study also allows for a direct comparison between results from paper-based tests and computerized tests, as well as between patients with right hemisphere lesions without neglect and USN patients. The secondary objectives are:
To compare these results in order to obtain a more refined definition of USN at both the unisensory level (as computerized tests are rarely used in hospital settings but have proven effective in diagnosing USN) and the multisensory level (since USN is not generally tested in the auditory modality).
To measure eye movements in all patients in the study, as this can provide useful information for characterizing patient deficits.
Who can participate
Age range
18 Years – 85 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients will be included in the study if they have:
* Right hemisphere stroke
* Presence of USN assessed through the Apple Cancellation
* Age between 18 and 85 years
* Signed informed consent
* Both male and female participants
As a control group, patients will also be included if they have:
* Right hemisphere stroke
* Absence of USN assessed through the Apple Cancellation
* Age between 18 and 85 years
* Signed informed consent
* Both male and female participants.
Exclusion Criteria:
* Both patients with USN and control patients will be excluded if they:
* Are minors
* Are unable to give their consent to participate in the study
* Have significant language deficits (production and comprehension) (e.g., unable to give a verbal response or understand instructions)
* Have hemianopia
* Have severe hearing impairments that cannot be corrected (e.g., with hearing aids)
* Have severe uncorrected visual impairments (e.g., glaucoma)
* Have a history of psychiatric disorders or substance abuse.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Multisensory Computerized Test
Timeframe: The assessment is conducted within a week of admission to the ward.
2
Multisensory Computerized Test
Timeframe: Is conducted over a total of three different days, during which the patient will complete Task 3 in three separate sessions, one for each day.