Bronchoscopic Microwave Ablation of Lung Tissue in Surgical Candidates (NCT06689488) | Clinical Trial Compass
RecruitingNot Applicable
Bronchoscopic Microwave Ablation of Lung Tissue in Surgical Candidates
Netherlands30 participantsStarted 2025-06-17
Plain-language summary
The overall purpose of this study is to characterise the clinical safety and performance of the Creo Medical MicroBlate™ Flex AB1 instrument in patients with pathologically confirmed malignancy eligible for surgical resection of their nodule, receiving bronchoscopic ablation prior to surgery.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Have signed informed consent.
. Subject is willing and able to comply with all aspects of the treatment and evaluation schedule.
. Are ≥ 18 years old.
. Have lung lesion(s)/nodule(s) which are histopathological-confirmed as cancer.
. Have soft tissue lung lesion(s):
. Are candidates for surgical resection as determined by a multi-disciplinary team (MDT) or tumour board.
. Greater than 10 mm of tumour-free lung parenchyma between target tumour and pleura or fissure.
. Subject is willing and able to comply with the study protocol requirements.
Exclusion criteria
. Have target nodule(s) within the International Association for the Study of Lung Cancer (IASLC) "Central Zone" (including bronchial tree, major vessels, heart, oesophagus, spinal cord, and phrenic \& laryngeal nerves).
. Are pregnant or breast feeding, as determined by standard site practices.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Primary Safety Endpoint
Timeframe: Day 0, day of ablation procedure up to initiation of surgical resection procedure.
2
Primary Safety Endpoint
Timeframe: Day 7-21, post ablation procedure up to initiation of surgical resection procedure.